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A patient on heparin therapy is found to have aPTT = 85 sec (control = 30 sec). He is stable and not bleeding. What should be the next step?
Question

A patient on heparin therapy is found to have aPTT = 85 sec (control = 30 sec). He is stable and not bleeding. What should be the next step?

A.

Stop heparin immediately and give protamine

B.

Continue same dose of heparin

C.

Increase the dose of heparin

D.

Switch to warfarin at once

Correct option is B

Therapeutic range of aPTT on heparin = 1.5–2.5 × control (≈45–75 sec). An aPTT of 85 is slightly above target but acceptable if no bleeding; hence, therapy can be continued with close monitoring.
Explanation of options: (a) ✘ Protamine is given only in bleeding or very high aPTT. (b) ✔ Correct; continue therapy as patient is stable, just monitor. (c) ✘ Increasing dose will push aPTT dangerously higher. (d) ✘ Switching to warfarin is long-term therapy, not immediate change here.

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