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Class 12 Biology Sample Paper 2023 with Answers PDF Solutions

Biology Sample Paper Class 12 2023

Biology Sample Paper Class 12 2023 is now available on Check here for Biology Sample Paper Class 12 2023 for getting good marks in Biology. The Central Board Of Secondary Education has introduced Sample Papers for students of classes 10 and 12 Board. These Sample papers are on its official website. Students can also download the sample papers from here given below.

CBSE has introduced sample papers for all the subjects according to the layout of the question paper which CBSE is going to implement in this session 2022-23. This time, CBSE has introduced only one term examination, which will be conducted in February 2023. Along with Biology Sample Paper Class 12 2023, CBSE also releases the Marking Scheme of Biology Sample Paper Class 12 2023. So that students can get a clear idea of the board exam format, question kinds, answer options, and other features with the help of Biology Sample Paper Class 12 2023.
In this article, we have covered the Biology Sample Paper Class 12 2023. The students must solve Biology Sample Paper Class 12 2023 which is given on this page and bookmark this page to get all the latest updates from CBSE regarding CBSE Annual Exam.

Biology Sample Paper Class 12 2023 with Solutions- Revision

CBSE Class 12 Additional Practice Question Paper 2023
CBSE Class 12 Physics Additional Practice Questions CBSE Class 12 Biology Additional Practice Questions
CBSE Class 12 Geography Additional Practice Questions CBSE Class 12 Accounts Additional Practice Questions
CBSE Class 12 Maths Additional Practice Questions CBSE Class 12 History Additional Practice Questions
CBSE Class 12 English Additional Practice Questions CBSE Class 12 Chemistry Additional Practice Questions

Biology Sample Paper Class 12 2023- Questions with Solutions

•Maximum Marks: 70

•Time: 3 hours
General Instructions:
(i) All questions are compulsory.
(ii) The question paper has five sections and 33 questions. All questions are compulsory.
(iii) Section–A has 16 questions of 1 mark each; Section–B has 5 questions of 2 marks each; Section– C has 7 questions of 3 marks each; Section– D has 2 case-based questions of 4 marks each; and Section–E has 3 questions of 5 marks each.
(iv) There is no overall choice. However, internal choices have been provided in some questions. A student has to attempt only one of the alternatives in such questions.
(v) Wherever necessary, neat and properly labeled diagrams should be drawn.


Biology Sample Paper Class 12 2023: Section- A

SECTION – A (1 mark each)

Q.1.An infertile couple was advised to undergo In vitro fertilization by the doctor. Out of the options given below, select the correct stage for transfer to the fallopian tube for successful results?
(a) Zygote only
(b) Zygote or early embryo upto 8 blastomeres
(c) Embryos with more than 8 blastomeres
(d) Blastocyst Stage

Q.2.Given below are four contraceptive methods and their modes of action. Select the correct match:

S. No. Method S. No. Mode of action
a) Condom (i) Ovum not able to reach Fallopian
b) Vasectomy (ii) Prevents ovulation
c) Pill (iii) Prevents sperm reaching the cervix
d) Tubectomy (iv) Semen contains no sperms

(a) a)–(i) b)–(ii) c)– (iii) d)–(iv)
(b) a)–(ii) b)–(iii) c)–(iii) d) – (i)
(c) a)–(iii) b)–(iv) c)–(ii) d)–(i)
(d) a)–(iv) b)–(i) c)– (iii) d)–(ii)

Q.3.Which of the following amino acid residues will constitute the histone core?
(a) Lysine and Arginine
(b) Asparagine and Arginine
(c) Glutamine and Lysine
(d) Asparagine and Glutamine

Q.4. Evolutionary convergence is development of a
(a) common set of functions in groups of different ancestry.
(b) dissimilar set of functions in closely related groups.
(c) common set of structures in closely related groups.
(d) dissimilar set of functions in unrelated groups.

Q.5. Apis mellifera are killer bees possessing toxic bee venom. Identify the treatment and the type of immunity developed from the given table to treat a person against the venom of this bee.

 Remedy Immunity
(a) Inactivated proteins Active
(b) Proteins of the venom Passive
(c) Preformed antibodies Passive
(d)  Dead micro-organisms Active

Q.6. Interferons are most effective in making non-infected cells resistant against the spread of which of the following diseases in humans?
(a) ascariasis
(b) ringworm
(c) amoebiasis
(d) AIDS
Q.7. Which of the following water samples in the table given below, will have a higher concentration of organic matter?

Water Sample Level of pollution  Value of BOD
(a) High High
(b) Low Low
(c) Low High
(d) High Low

8. The figure below shows the structure of a plasmid.

A foreign DNA was ligated at BamH1. The transformants were then grown in a medium containing antibiotics tetracycline and ampicillin.Choose the correct observation for the growth of bacterial colonies from the given

Medium with Tetracycline with Ampicillin
(a) Growth No growth
(b) No Growth Growth
(c) No Growth No Growth
(d) Growth Growth

Q.9. Swathi was growing a bacterial colony in a culture flask under ideal laboratory conditions where the resources are replenished. Which of the following equations will represent the growth in this case?
(Where population size is N, birth rate is b, death rate is d, unit time period is t, and carrying capacity is K).
(a) dN/dt = KN
(b) dN/dt = r N
(c) dN/dt = r N(K-N/K)
(d) dN/dt = r N(K+N/K)

Q.10. Sea Anemone gets attached to the surface of the hermit crab. The kind of population interaction exhibited in this case is
(a) amensalism.
(b) commensalism.
(c) mutualism.
(d) parasitism


Q.11. Which of the following food chains is the major conduit for energy flow in terrestrial and aquatic ecosystems respectively?

Terrestrial Ecosystem Aquatic Ecosystem
(a) Grazing Grazing
(b) Detritus Detritus
(c) Detritus Grazing
(d) Grazing Detritus

Q.12, Which of the following is an example of ex situ conservation?
(a) Sacred Groves
(b) National Park
(c) Biosphere Reserve
(d) Seed Bank
Question No. 13 to 16 consist of two statements – Assertion (A) and Reason (R). Answer these questions selecting the appropriate option given below:              
A. Both A and R are true and R is the correct explanation of A.
B. Both A and R are true and R is not the correct explanation of A.
C. A is true but R is false.
D. A is False but R is true.

Q.13. Assertion: Apomictic embryos are genetically identical to the parent plant.
Reason: Apomixis is the production of seeds without fertilization.

Q.14. Assertion: When white eyed, yellow bodied Drosophila females were hybridized with red eyed, brown-bodied males; and F1 progeny was intercrossed, F2 ratio deviated from 9 : 3 : 3 : 1.
Reason: When two genes in a dihybrid are on the same chromosome, the proportion of parental gene combinations is much higher than the non-parental type.

Q.15. Assertion: Functional ADA cDNA genes must be inserted in the lymphocytes at the early embryonic stage.
Reason: Cells in the embryonic stage are mortal, differentiated and easy to manipulate.

Q.16. Given below is the Age Pyramid of population in one of the states in India as per 2011 census. It depicts the male population on the left hand side, female population on the right hand side, newborns towards the base and gradually increasing age groups as we move from base to the top, with the oldest population at the top. Study this pyramid and comment upon the appropriateness of the Assertionand the Reason

Assertion: It is a stable population.
Reason: The pre-reproductive and reproductive individuals are almost in equal numbers and the post-reproductive individuals are relatively fewer.

Biology Sample Paper Class 12 2023: Section- B

SECTION – B (2 mark each)

Q.17. In the figure given below, parts A and B show the level of hormones which influence the menstrual cycle. Study the figure and answer the questions that follow:

a) Name the organs which secrete the hormones represented in parts A and B.
(b) State the impact of the hormones in part B on the uterus of the human female during 6 to 15 days of menstrual cycle?
Q.18. A true breeding pea plant, homozygous dominant for inflated green podsis crossed with another pea plant with constricted yellow pods (ffgg). With the help of punnett square show the above cross and mention the results obtained phenotypically and genotypically in F1 generation?

Q.19. During a field trip, one of your friend in the group suddenly became unwell, she started sneezing and had trouble in breathing. Name and explain the term associated with such sudden responses. What would
the doctor recommend for relief?

(a) What are such sequences called? Name the enzyme used that recognizes
such nucleotide sequences.
(b) What is their significance in biotechnology?
Q.21. (a) Given below is a pyramid of biomass in an ecosystem where each bar represents the standing crop available in the trophic level. With the help of an example explain the conditions where this kind of pyramid is possible in nature?

(b) Will the pyramid of energy be also of the same shape in this situation? Give reason for your response.
(a) Draw a pyramid of numbers where a large number of insects are feeding on the leaves of a tree. What is the shape of this pyramid?
(b) Will the pyramid of energy be also of the same shape in this situation? Give reason for your response.

Biology Sample Paper Class 12 2023: Section- C

SECTION – C (3 mark each)

Q.22. Explain the functions of the following structures in the human male reproductive system.
(a) Scrotum
(b) Leydig cells
(c) Male accessory glands
Q.23. State the agent(s) which helps in pollinating in the following plants. Explain the
adaptations in these plants to ensure pollination:
(a) Corn
(b) Water hyacinth
(c) Vallisneria
Q.24. (a) Identify the polarity of x to x’ in the diagram below and mention how many more amino acids are expected to be added to this polypeptide chain.

(b) Mention the codon and anticodon for alanine.
(c) Why are some untranslated sequences of bases seen in mRNA coding for a polypeptide? Where exactly are they present on mRNA?
Q.25. (a) How is Hardy-Weinberg’s expression “(p²+ 2pq+q²) = 1”derived?
(b) List any two factors that can disturb the genetic equilibrium.

Q.26. Highlight the structural importance of an antibody molecule with a diagram. Name the four types of antibodies found to give a humoral immune response, mentioning the functions of two of them you have studied.
(a) Explain the Life cycle of Plasmodium starting from its entry in the body of female Anopheles till the completion of its life cycle in humans.
(b) Explain the cause of periodic recurrence of chill and high fever during malarial attack in humans.
Q.27. Carefully observe the given picture. A mixture of DNA with fragments ranging from 200 base pairs to 2500 base pairs was electrophoresed on agarose gel with the following arrangement.

(a) What result will be obtained on staining with ethidium bromide? Explain with reason.
(b) The above set-up was modified and a band with 250 base pairs was obtained at X.

What change(s) were made to the previous design to obtain a band at X? Why did the band appear at the position X?
Q.28 (a) There was loss of biodiversity in an ecosystem due to a new construction project in that area. What would be its impact on the ecosystem? State any three.
(b) List any three major causes of loss of biodiversity?

Biology Sample Paper Class 12 2023: Section- D

SECTION – D (4 mark each) 29 and 30 are case based questions. Each question has subparts with internal choice in one subpart.
Q.29. Study the Pedigree chart given below and answer the questions that follow:

(a) On the basis of the inheritance pattern exhibited in this pedigree chart, what conclusion can you draw about the pattern of inheritance?
(b) If the female is homozygous for the affected trait in this pedigree chart, then what percentage of her sons will be affected ?

(c) Give the genotype of offsprings 1,2,3 and 4 in III generation.
(c) In this type of inheritance pattern, out of male and female children which one has less probability of receiving the trait from the parents. Give a reason.

Q.30. The data below shows the concentration of nicotine smoked by a smoker taking 10 puffs/ minute.

(a) With reference to the above graph explain the concentration of nicotine in blood at 10 minutes.
(b) How will this affect the concentration of carbon monoxide and haembound oxygen at 10 minutes?
(c) How does cigarette smoking result in high blood pressure and increase in heart rate?
(c) How does cigarette smoking result in lung cancer and emphysema?

Biology Sample Paper Class 12 2023: Section- E

SECTION – E (4 mark each)

Q.31. Trace the events from copulation to zygote formation in a human female.
Trace the development of a megaspore mother cell to the formation of mature embryo sac in a flowering plant.
Q.32. Observe the segment of mRNA given below.

(a) Explain and illustrate the steps involved to make fully processed hnRNA?
(b) Gene encoding RNA Polymerase I and III have been affected by mutation in a cell. Explain its impact on the synthesis of polypeptide, stating reasons.
Study the schematic representation of the genes involved in the lac operon given below and answer the questions that follow:

(a) The active site of enzyme permease present in the cell membrane of a bacterium has been blocked by an inhibitor, how will it affect the lac operon?
(b) The protein produced by the i gene has become abnormal due to unknown reasons. Explain its impact on lactose metabolism stating the reason.
(c) If the nutrient medium for the bacteria contains only galactose; will operon be expressed? Justify your answer.

Q.33. Oil spill is a major environmental issue. It has been found that different strains of Pseudomonas bacteria have genes to break down the four major groups of hydrocarbons in oil. Trials are underway to use different biotechnological tools to incorporate these genes and create a genetically engineered strain of Pseudomonas
– a ‘super-bug’, to break down the four major groups of hydrocarbons in oil. Such bacteria might be sprayed onto surfaces polluted with oil to clean thin films of oil.
(a)  List two advantages of using bacteria for such biotechnological studies?
(b) For amplification of the gene of interest PCR was carried out. The PCR was run with the help of polymerase which was functional only at a very low temperature. How will this impact the efficiency of the PCR? Justify.
(c) If such bacteria are sprayed on water bodies with oil spills, how will this have a positive or negative effect on the environment? Discuss.
Insects in the Lepidopteran group lay eggs on maize crops. The larvae on hatching feed on maize leaf and tender cob. In order to arrest the spread of three such Lepidopteran pests, Bt maize crops were introduced in an experimental field.
A study was carried out to see which of the three species of lepidopteran pests was most susceptible to Bt genes and its product.

The lepidopteran pests were allowed to feed on the same Bt-maize crops grown on 5 fields (A-E).
The graph below shows the leaf area damaged by these three pests after feeding on maize leaves for five days.

(a) Evaluate the efficacy of the Bt crop on the feeding habits of the three species of stem borer and suggest which species is least susceptible to Bt toxin.
(b) Which species is most susceptible to Bt-maize, explain why?
(c) Using the given information, suggest why similar effect was not seen in the three insect species?

Class 12 Biology Sample Paper 2022-23 with Solutions PDF

Here we are given the  CBSE Class 12 Biology Sample Question Paper 2023 in pdf format. Students can download and take a print of CBSE Class 12 Biology Sample Question Paper 2023. Check CBSE Class 12 Biology Sample Paper 2023 PDF Download on Adda247

CBSE Class 12 Biology Sample Question Paper 2023 – SQP


Class 12 Biology Sample Paper 2023: Marking Scheme

Check CBSE Class 12 Biology Sample Paper 2023 Marking Scheme on Adda247

CBSE Class 12 Biology Sample Question Paper 2023 Marking Scheme

CBSE Class 12 Sample Papers 2022-23

CBSE Class 12 Business Studies Sample Paper 2023 CBSE Class 12 Economics Sample Paper 2023 CBSE Class 12 History Sample Paper 2023
CBSE Class 12 Accountancy Sample Paper 2023 CBSE Class 12 English Core Sample Paper 2023 CBSE Class 12 Informatics Practices Sample Paper 2023
CBSE Class 12 Chemistry Sample Paper 2023 CBSE Class 12 English Elective Sample Paper 2023 CBSE Class 12 Biology Sample Paper 2023
CBSE Class 12 Computer Science Sample Paper 2023 CBSE Class 12 Geography Sample Paper 2023 CBSE Class 12 Mathematics Sample Paper 2023
CBSE Class 12 Physical Education Sample Paper 2023 CBSE Class 12 Physics Sample Paper 2023 CBSE Class 12 Psychology Sample Paper 2023
CBSE Class 12 Sociology Sample Paper 2023 CBSE Class 12 Hindi Elective and Core Sample Paper 2023




Where can I get CBSE Class 12 Biology Sample Question Paper 2023?

The Central Board of Secondary education has released CBSE Class 12 Biology Sample Question Paper 2023 at On this page, we provide CBSE Class 12 Biology Sample Question Paper 2023 pdf. You can download it from the page.

Does CBSE cut marks for handwriting?

Although it is important to write in legible handwriting but students will not get any extra marks for good handwriting.

Do the exam evaluators give marks based on a good presentation on the answer sheet?

No, there is no provision to give marks for a good presentation. However, students should concentrate on writing well-structured, neat, and highlighted answers. Students can also see the CBSE toppers answer sheet to learn how to write an answer.


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